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Arginine should also be used carefully in patients with significant renal impairment or vere hepatic disease

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Semaglutide effects on cardiovascular outcomes in people with overweight or obesity (SELECT) rationale and design

Chronic conditions impacting absorption include atrophic gastritis or pernicious anaemia, where there is a lack of intrinsic factor, a protein essential for the uptake of B12 in the digestive tract

Medications that can interfere with B12 include metformin, proton pump inhibitors, and H2 blockers
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