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For the OGD phase, cells were washed twice with PBS and then incubated in glucose-free DMEM (Gibco, Thermo Fisher Scientific, Waltham, MA, United States) under hypoxic conditions (1% O 2 , 94% N 2 , 5% CO 2 ) in a hypoxia chamber (BioSpherix, Parish, NY, United States) for 8 h

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Dikeman et al., 2005) but according to Samsudin and Abdullah, mushrooms have both digestible carbohydrates such as glucose, mannitol, glycogen, and trehalose as well as non-digestible carbohydrates such as mannans, -glucans and chitin (Samsudin and Abdullah, 2019)