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In vivo , chronic treatment with opioids promotes decrease (down-regulation), no change or increase (up-regulation) of OR (Bernstein and Welch, 2001
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This is the first report about the distribution of aluminum, potassium, hydrangea blue-complex, and copigment in sepal tissues and the first evidence that aluminum and hydrangea blue-complex exist in blue sepal cells and are involved in blue coloration
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over ~1 mg/day shows no added benefit in references
