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doi: 10.1146/annurev-biophys-060414-034156

Weight loss as the dominant liver-directed mechanism Pulling these threads together, the most defensible model is that CagriSemas potential liver benefit would be driven predominantly by the sheer size and durability of weight loss it produces, layered on top of semaglutides established metabolic effects, with amylin agonism contributing mainly by amplifying and maintaining that weight loss

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DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA

doi: 10.1073/pnas.0508052102