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[PubMed] [Google Scholar] 190.Clarkson C.W., Hondeghem L.M

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Members of the Pernicious Anaemia Society forum have proposed: Many people on this forum have said that B12 injections made their symptoms worse

It is stable against proteolytic digestion and its activity is almost not affected by physiological salt concentration [182]

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Some symptoms of a vitamin B12 deficiency include: difficulty thinking brain fog fatigue pale skin weight loss dementia numbness and tingling in hands and feet mood changes decreased appetite constipation A lack of animal protein and following a plant-based diet sans appropriate supplementation can lead to a vitamin B12 deficiency