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Lower DSIP levels have been correlated with depressive states, suggesting its involvement in hypothalamic-pituitary-adrenal (HPA) axis modulation ( 11 )

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Over time, this may be reduced to bi-weekly or monthly treatments, based on how your body responds and your ongoing wellness needs

This dual mechanism is what makes tirzepatide more effective than single-agonist medications

doi: 10.1038/nrm.2017.53 82 HanahanDWeinbergRA