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In a 2017 bioavailability study, methylcobalamin supplementation (1,000 mcg/day) led to 13% higher liver retention and lower urinary loss compared to cyanocobalamin, translating to sustained energy in deficient adults

Nutrition and cancer, 64(7), 11221130

Table 1: Vitamin B12 treatment methods compared in this study The effectiveness of both vitamin B12 supplementation methods In both groups, vitamin B12 deficiencies were treated for all patients over the course of 6 months, showing no significant difference in concentration between oral or intramuscular supplementation

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