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Evidences associating pineal gland function with alterations in pigmentation

(2023) employed response surface methodology (RSM) integrated with genetic algorithmartificial neural network (GAANN) modeling, identifying optimal conditions as follows: 52 C, 1:30 solidliquid ratio (w/v), 167 min duration, and 0.01 mol/L NaOH, yielding 29.53% BSP recovery

PMID 26731792

explored the protective effect of MO seed oil against gentamicin-induced pro-inflammation in rats (Verma et al., 2012

And a plasma-activated medium (PAM) also promotes cell death by depleting FSP1 in human lung cancer cells and increasing intracellular lipid ROS [109]

Together, these finding indicate that the toxic effects of DOX on the heart are strongly associated with iron overload and ferroptosis in mitochondria, indicating that targeting ferroptosis could serve as a promising therapeutic strategy for protecting the hearts of cancer patients from DOX-induced cardiomyopathy