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Library preparation and sequencing were performed, followed by the trimming of sequence reads using fastp v.0.23.13 to remove potential adaptor sequences and low-quality nucleotides

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Rare: may affect up to 1 in 1,000 people Acniform and bullous eruptions (acne-like and blistery skin eruptions) Not known: frequency cannot be estimated from the available data Headache, dizziness Nausea (feeling sick), vomiting, diarrhoea Malaise (feeling unwell) Rash, itching Injection site reactions including injection site pain, injection site erythema, injection site pruritus, injection site induration, and injection site swelling (Reactions at the site of the injection) Exanthema (a widespread skin rash) Chromaturia (unusual coloured urine) Fever Hot flushes (a feeling of intense heat with sweating and rapid heartbeat) Chills (feeling of coldness accompanied by shivering) Paraesthesia (feeling of pins and needles) Tremor (tremble or shakes) Hypokalaemia (decreased potassium levels in the blood) Reactive thrombocytosis (body produces too many platelets) Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse

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Individual response can vary, and many practitioners recommend starting conservatively and adjusting based on observed results

Personal stories may help identify promising areas for research, but they are not a substitute for controlled clinical studies