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Description
Neuromelanin accumulates in double membrane vacuoles, preventing neurotoxic effects of free neuromelanin in cells exposed to this pigment [29, 30]

10.1016/j.neurobiolaging.2011.09.021 Neurobiol

Cushing, T

What it does in that 55-year-old patient at that dose for that injury remains unanswered
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A control group was assigned to follow a low-calorie diet

Consequently, while existing therapeutic strategies show promise in pre-clinical models, significant challenges such as organ specificity, potential off-target effects, and inter-individual metabolic variability must be addressed prior to clinical translation
