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Research shows that low B12 levels are associated with increased body fat, disrupted fat processing and insulin resistance, highlighting its role in maintaining metabolic balance

Consequently, low levels of intracellular vitamin C mediate the reduction of antioxidants like nicotinamide adenine dinucleotide phosphate (NADPH) and superoxide dismutase (SOD) enzyme

Han Z, Wang Q, Wu X, Wang J, Gao L, Guo R, et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 62.Sequeira I.R., Woodhead J.S.T., Chan A., DSouza R.F., Wan J., Hollingsworth K.G., Plank L.D., Cohen P., Poppitt S.D., Merry T.L

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Neutrophils are signaled to the areas of inflammation even without infection present, but bacterial presence can push this neutrophilic response further, generating more oxidative stress from released reactive oxygen species, more crosslinking of the mucins from the oxidative stress, and more DNA released from dying epithelial and neutrophil cells (Yuan et al., 2015