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A possible relationship between endocytosis, tolerance, and addiction risk is still being resolved (Berger and Whistler, 2010)

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The intensity of the response was reported to be roughly proportional to the length of exposure time (1 - 60 min) and the concentration (Hollingsworth et al., 1956)

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In parallel, an experimental treatment of 6-gingerol on mice induced with lupus showed reductions in the levels of the pro-inflammatory TNF- and IFN- isotypes, pointing to its good effects on SLEs usual general inflammation aspects (162)

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