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In line with these insights, it has been observed that PKM2 represses ferroptosis, evidence by increased cell viability and GPX4 expression and reduced levels of lipid ROS and ferritin heavy chain (FTH) [33]

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Apoptosis and Necrosis Cardiac IRI induces different types of cell death mechanisms, including apoptosis and necrosis, highlighting their significant impact on clinical outcomes

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FSP1: A key regulator of ferroptosis
