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167 , 168 Currently, CD38 antibodies are also combined with PIs such as carfilzomib and bortezomib, however the exact mechanisms by which these combinations exert their efficacy are less clear than combinations with IMiDs

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PMID 19237716

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Boosting it could extend healthy lifespan."[13][3] He advocates for precursors but sees value in inhibitors like 5-Amino-1MQ to maximize NAD+ utility