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The latter is considered a principal component of the antioxidant mechanism, and it has been acknowledged that it impairs the function of NRF-2 in many liver diseases and that it forms an essential part of the pathologic changes that occur in the liver to contain inflammation and damage

Astaxanthin treatment confers protection against oxidative stress in U937 cells stimulated with lipopolysaccharide reducing O2 production

Methionine and neural tube closure in cultured rat embryos: morphological and biochemical analyses

ABBREVIATIONS ABC ATP-binding cassette transporters APK adenosine-5-phosphosulfate kinase APS adenosine-5-phosphosulfate BAT or BASS bile acid transporter BCAT branched-chain amino acid aminotransferase CHS chalcone synthase CF conjugated flavonoids CLT chloroquine-resistance transporter (CRT)-like transporters Cys cysteine -EC -glutamylcystein GGT gamma-glutamyl transpeptidase GSH glutathione GSL glucosinolates GST glutathione-S-transferase GTR glucosinolate transporter H 2 S hydrogen sulfide IMPI isopropylmalate isomerase IPM-DH isopropylmalate dehydrogenase Leu leucine MAM methylthioalkylmalate synthase MATE multidrug and toxic compound extrusion Met methionine MDR multidrug resistance family of transporters MRP multidrug resistance-associated protein MTOB 4-methylthio-2-oxobutanoate NRT/PTR nitrate and peptide transport family OAS O -acetylserine OASTL O-acetylserine (thiol)lyase PAs proanthocyanidins PAP 3-phosphoadenosine 5-phosphate PAPS 3-phosphoadenosine-5-phosphosulfate PAPST1 3-phosphoadenosine-5-phosphosulfate transporter PC phytochelatins PDR pleiotropic drug resistance PSK disulfated pentapeptide phytosulfokine PSY1 peptide containing sulfated tyrosine 1 RGFs root growth factors (peptides containing sulfated tyrosine) S sulfur SAM S-adenosylmethionine SAMT SAM transporter SMM S-methylmethionine SLC13 sodium/sulfate co-transporter SLC26 sulfate/anion (A - ) exchanger SLIM1 transcription factor Sulfate Limitation 1 SOT sulfotransferase STAS domain found in sulfate transporters with a significant similarity to bacterial anti-sigma factor antagonists SULTR plant sulfate transporters SURE sulfur-responsive element in the promoters of genes TGN trans Golgi network TPST tyrosylprotein sulfotransferase tt transparent testa mutants Val valine YCT1 cysteine transporter 1MO-I3M 1-methoxy-indole-3-ylmethyl-glucosinolate 4MO-I3M 4-methoxy-indole-3-ylmethyl-glucosinolate

In contrast, participants with the TOLLIP CC genotype (about 25% of the cohort) showed a trend toward harm from NAC treatment

Teixeira et al., 2020a)