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The second exception is when a bovine is apparently very sick from either a gut disorder that may have wreaked havoc on their rumen microbial communities (like what acidosis can do) or are suffering from serious cobalt/B12 deficiency

Meanwhile, western blot results indicated that the vitamin B12-treated groups showed reduced levels of cleaved-caspase12 expression relative to their untreated counterparts in Figure 2B,C
