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X-ray crystal structure of LET7 showing autoinhibition of the catalytic LET7 PPase domain (green) by binding to the N-terminal TPR domain (blue) (PDB code: 7OBE) (right panel)

10.1111/FEBS.17137 [DOI] [PubMed] [Google Scholar] Laroche C, Gervais P (2003) Achievement of rapid osmotic dehydration at specific temperatures could maintain high Saccharomyces cerevisiae viability

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This substantial participant database provides meaningful safety evidence across varied dosing regimens, administration routes (oral and injectable), and treatment durations, making it one of the more extensively studied peptide fragments in human clinical trials
