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The highest relative expression of the CAT gene was observed under Cd + NaHS treatment, followed by Cd + MG + NaHS, Cd + MG, and Cd treatments (Fig

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238 Inhibiting the demethylase activity of FTO with Rhein can sensitize resistant cells to TKIs, downregulate Bcl-2 and MER proto-oncogene, tyrosine kinase (MERTK), thus regulating the PI3K-AKT-mTOR pathway and the Bcl-2 family of proteins, which affects the invasion and apoptosis of cancer cells

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