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and several synthetic vitamin A derivatives such as adapalene and tazarotene

Moreover, ApoE4 M showed a more spread and skewed distribution

10.1186/s12984-020-00718-x 41 De AngelisM.LavorgnaL.CarotenutoA.PetruzzoM.LanzilloR.Brescia MorraV.et al

Notably, collagen-IV downregulation was observed in APOE4 models within the occludin/ECM pathway
