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In expressions (15), l is defined as any arbitrary one-dimensional length of the brain (for example, rostro-caudal length of the brain), used only for defining the one-dimensional proportion (l2/l1) between two observed brains (or veins or heart) and as an inter-factor (and because of that, it is not measured [6]) for deriving final expression (6)

Its oral bioavailability (1 ER) is therefore expected to be about 33%, which is close to the observed value ( Table 31 )