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Maurer DM, Raymond TJ, Davis BN

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Thus, acute, membrane-localized ROS is a prerequisite for effector function

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This current report aims to review the literature underlying all these insights and present an up-to-date perspective on the current understanding of GPX4 as a potential therapeutic target

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MIG (CXCL9) and IP-10 (CXCL10) are involved in Th1, CD8, and NK cell migration and early upregulation after SARS-CoV-2 infection (73)

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2.3.2 Takeda G protein-coupled Receptor 5: a complex regulator of inflammatory responses and cell function Distinct from the nuclear receptor FXR discussed previously, Takeda G protein-coupled Receptor 5 (TGR5, or GPBAR1) serves as a primary cell surface sensor for secondary bile acids (SBAs), particularly lithocholic acid (LCA) and deoxycholic acid (DCA), which are generated through gut microbial metabolism (77)

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Nardini M, Scaccini C, Packer L, Virgili F

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