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Maurer DM, Raymond TJ, Davis BN

Thus, acute, membrane-localized ROS is a prerequisite for effector function

This current report aims to review the literature underlying all these insights and present an up-to-date perspective on the current understanding of GPX4 as a potential therapeutic target

MIG (CXCL9) and IP-10 (CXCL10) are involved in Th1, CD8, and NK cell migration and early upregulation after SARS-CoV-2 infection (73)

2.3.2 Takeda G protein-coupled Receptor 5: a complex regulator of inflammatory responses and cell function Distinct from the nuclear receptor FXR discussed previously, Takeda G protein-coupled Receptor 5 (TGR5, or GPBAR1) serves as a primary cell surface sensor for secondary bile acids (SBAs), particularly lithocholic acid (LCA) and deoxycholic acid (DCA), which are generated through gut microbial metabolism (77)

Nardini M, Scaccini C, Packer L, Virgili F
