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fossilis, exposure to 4-Nonylphenol (4-NP) results in a dose-dependent decrement of antioxidant enzymes including Superoxide dismutase(SOD), Catalase, and Glutathione peroxidase(GPx), alongside a dose and duration-dependent increase in Lipid peroxidation (LPO) levels

Mitochondrial dysfunction induces an imbalance between oxidation and antioxidation, mitochondrial DNA (mtDNA) damage, mitochondrial dynamics dysregulation, and changes in mitophagy

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This argument is backed by scientific evidence collected over many years and multiple countries using crash data and fatality data

Its very low bioavailability limits the interest of a supplementation

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