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GSH also acts as an enzyme cofactor for GPx to degrade H 2 O 2 and hydroperoxides (ROOH), and is involved in detoxifying electrophilic xenobiotics via GSH- S -transferase (GST) [43] (Figure 2)

miR-21/BDH2 pathway was found to promote iron accumulation during Tfh cell differentiation, further enhancing Fe2+ -dependent TET enzyme activity and BCL6 gene demethylation [26]

IGF-1 is also expressed in skeletal muscle, particularly following exercise, playing a crucial role in muscle growth, differentiation and regeneration [155]

Longo et al., 2024)

It is important to avoid sun exposure when using skin lightening creams, as they increase photosensitivity and this can cause skin irritation or even lead to the exacerbation of hyperpigmentation

Zinc deficiency disrupts DNA replication and transcription, resulting in aberrant gene expression that compromises cell division, growth, and development [3]