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One molecule of GSH reduces the selenenic acid, leading to the formation of a glutathiolated selenol (Se-SG) intermediate (127, 204, 248)

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During lipid peroxidation, the PUFAs that make up the membrane phospholipids lose bis-allylic hydrogen atoms, resulting in the formation of phospholipid radicals (PL) [34]

Although some studies indicate that ethnic and environmental factors, in addition to genetic factors, can also influence on disease progression, the caution should be exercised in drawing too hasty conclusions