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In normal cellular physiology, IGFs exert their effects through endocrine, paracrine, and autocrine mechanisms by binding to their receptors to activate signaling pathways that promote cell proliferation and inhibit apoptosis

doi: 10.31989/ffhd.v12i4.912

*Correspondence: Hongru Zhang, [email protected]

The previous findings of our lab (32) and others (33) have demonstrated that brain GSH concentration in older adults is significantly lower than in younger adults by over 10%

As Table 4 shows, the concentration of IGF and cortisol was more than two-fold higher in hPL (125 g/L, 72.877.3 g/L) than in FBS (4072 g/L, 20 g/L), which may impact the efficacy of cell-based therapies if hormonal regulation is present (Peters et al., 2022

it was able to prevent the occurrence of pain secondary to both the acute and chronic OIPN (NCT01450163)