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Another obstacle to peptide therapeutics is their limited ability to cross biological membranes and cellular barriers [2]

The protocol for this study, including doses of vitamin B 12 and diclofenac were designed according to previous studies in which 0.02-2 mg kg -1 once and 0.5 mg kg -1 for 7-14 days of vitamin B 12 and 1-10 mg kg -1 once and 5 mg kg -1 for 7-14 days of diclofenac were used

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