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Novel impact of the DNMT3A R882H mutation on GSH metabolism in a K562 cell model established by TALENs

For example, the reaction between 4-fluorothalidomide (2) and tert-butyl-2-aminoacetate or the reaction between pomalidomide and tert-butylbromoacetate results in the introduction of an acetamide group (33) , which facilitates the attachment of a linker with an amine terminus via the formation of an amide bond (35) (Scheme 5) 68,90

doi: 10.1016/j.jep.2018.12.036

SGV acknowledges the support of National Medical Research Council of Singapore grant MOH-001497-00

[DOI] [PubMed] [Google Scholar] [63].Goto S, Iida T, Cho S, Oka M, Kohno S, Kondo T

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