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and 1.5, 2, 3, 4, 5, 6, 7, 8 10, 12, 18, and 24 hours after the dose

Mouse zygotes were collected from superovulated donors, electroporated with Cas9/gRNA and a single strand DNA donor containing the E116A mutation and then transferred to surrogate females to generate founder animals

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suum L3 to various stress conditions including heat, methanol, and anthelmintics, and investigated their impact on larval metabolism through resazurin reduction activity

Subsequent somatic loss of the remaining allele results in disease manifestations such as peripheral nerve sheath tumors of the Schwann cell ontology, aberrant bone formation/reabsorption, and low-grade gliomas of the brain, as well as other tumors of neural crest-derived tissues [1,2]