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However, deficiency of ascorbate dysregulates glutamate clearance leading to its accumulation and ultimately excitotoxicity of neurons that contributes to cognitive impairment ( Vitamin C and Alzheimers disease The formation and deposition of neurofibrillary tangles and A plaques are characteristics of an AD patients brain
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Perry T, Lahiri DK, Chen D, Zhou J, Shaw KTY, Egan JM, Greig NH (2002) A Novel Neurotrophic Property of Glucagon-Like Peptide 1: A Promoter of Nerve Growth Factor-Mediated Differentiation in PC12 Cells
