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The repeat bone marrow biopsy showed normocellular bone marrow and no evidence of any leukemia or lymphoma (Figure 2)

10.3390/ijms141021021 13

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10.1073/pnas.0308291101 401

These timelines represent general patterns rather than guarantees

Single-cell transcriptomic analyses reveal significant gene expression alterations in oligodendrocyte lineage cells during early AD stages (240), with myelination-related pathways consistently disrupted across multiple cell types in prefrontal cortical tissues, underscoring myelination's pivotal role in AD pathophysiology (240)
