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Interv Aging , 757772 (2018)

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It applies when sudden, rapid blood loss from a specific event causes anemia

However, current research is constrained by uneven evidence quality, inconsistent findings due to multidimensional heterogeneity, and insufficiently clarified direct molecular targets

Further involved in estrogen activity , ESR1 and ESR2 encode estrogen receptor alpha (ERalpha) and beta (ERbeta)

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