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The Keap1-Nrf2 system prevents onset of diabetes mellitus

In conclusion, the frequent occurrence of immune abnormalities amongst crew members during low-earth orbit flights and the inability to predict which specific crew members will suffer such alterations provide clinical challenges for future missions to Mars
[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Ichikawa Y, Ghanefar M, Bayeva M, Wu R, Khechaduri A, Naga Prasad SV, Mutharasan RK, Naik TJ, Ardehali H

The clinician should also maintain a level of suspicion regarding the potential for hepatotoxicity in newly marketed drugs that have not yet been used widely in the population, where idiosyncratic reactions are often first detected

Arthritis Rheum (2008) 58:300919
cautious use of the ophthalmic solution is advised with ocular surgery (3, 5)
