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The Livers Processing Limit: Normally, a liver enzyme known as FMO3 converts TMA into an odorless compound called trimethylamine-N-oxide (TMAO) [10] [11]

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Intern Med 57:35933596

Because KAT6A contains multiple functional domains, it is possible that ARTHS variants may result in a truncated protein that retains acetyltransferase activity but lacks proteinprotein interaction domains that regulate this activity