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These data indicate that different dopamine receptor subtypes mediate both pro-and anti-inflammatory activity in the gut and may act differently on discrete types of immune cells, as D5 activation was shown to both decrease colitis by altering M1/M2 ratios and increase T h 1/T h 17-mediated inflammation

Angelov, L., Salhia, B., Roncari, L., McMahon, G

Yin X, Yu H, Jin X, Li J, Guo H, Shi Q, Yin Z, Xu Y, Wang X, Liu R, Wang S, Zhang L

Fandohan P, Zoumenou D, Hounhouigan DJ, Marasas WF, Wingfield MJ, Hell K

H., Wu K

pp 350
