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However, vegan and vegetarian diets are low in carnitine, often providing only 1012 mg daily
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L-carnitine increases cell proliferation and amino acid transporter expression via the activation of insulin-like growth factor I signaling pathway in rat trophoblast cells

This pathway is the major source of energy for the heart [120]

Safety of L-Carnitine Carnitine is relatively well-tolerated but in high doses it may increase levels of trimethylamine-N-oxide (TMAO), a compound linked with an heart disease since it can increase blood pressure and the formation of plaque within the artery walls (atherosclerosis) (9)

An early trial in 160 men and women diagnosed with a recent MI showed that oral L-carnitine (4 g/day) in addition to standard pharmacological treatment for one year significantly reduced mortality and the occurrence of angina attacks compared to the control (47)