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Mean heteroplasmic SNV count as a function of mtCN in UKB and AoU
Briefly, cells were cultured for 4 h in glucose-free DMEM medium containing 10% delipidated serum (VivaCell, C3840) and [U- 13 C]PA ( m + 16) (Cambridge Isotope Laboratories, 56599-85-0) (20 M for Huh7, 50 M for H1299)
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They combine specifically coordinated substances with their natural co-factors, which complement and activate each other
