glutathione degradation ferroptosis CHAC1 of enhances cystine-starvation-induced necroptosis and in human triple negative breast cancer cells via the GCN2-eIF2α-ATF4 pathway Ferroptosis: a regulated cell death

These may include: Mild redness around the puncture point Temporary swelling due to fluid introduction Tenderness or itching as the tissue responds Minor bruising from the needle piercing small blood vessels These reactions are often temporary and subside on their own

doi: 10.1371/journal.pbio.1002533 191 ShengZ.XuJ.WangM.XuX.ZhuJ.ZengS.et al

When these algae experience stress such as intense sunlight, nutrient scarcity, or high salinity they begin producing astaxanthin as a shield to protect their cells from oxidative damage.16 Many marine animals feed on these algae, such as:17 Salmon Shrimp Krill Trout Flamingos These animals absorb and store the pigment in their tissues, which gives them their distinctive pink or reddish coloration.18 What makes astaxanthin compelling is that the same compound algae use to shield their cells from light, heat, and environmental stress may also help human cells withstand similar challenges

Wilson's disease causes copper accumulation due to impaired excretion

IL31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

This research was funded by the Polish National Science Center, NCN 2021/43/D/NZ3/00428