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Description

It has shown good efficacy in the treatment of malignant tumours, such as prostate cancer, breast cancer, and chronic lymphocytic leukaemia [129]

These effects are strongly supported by molecular findings, such as the upregulation of anabolic pathways (mTORC1) and the downregulation of catabolic and autophagic signaling, as well as reduced tumor progression

Additionally, clinical trials investigating intermittent claudication have reported therapeutic effects consistent with ALDH2 isozyme functions, such as improved ischemic tolerance, angiogenesis and mitochondrial metabolism (172,173)

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