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Targeting pyruvate kinase M2 and hexokinase II, pachymic acid impairs glucose metabolism and induces mitochondrial apoptosis
The microsomal pellets were finally resuspended in 0.1 M phosphate buffer (pH 7.4) and kept in deep freezing at -80C
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Blood 97 , 31463151 (2001)
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However, exclusion criteria included active substance abuse or dependence, dementia, current psychotic symptoms, suicidality requiring hospital care, and bipolar disorder
