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In: Ozone

J Biol Chem 254: 49824992

Stimulation of the Fibrillar Collagen and Heat Shock Proteins by Nicotinamide or Its Derivatives in Non-Irradiated or UVA Radiated Fibroblasts, and Direct Anti-Oxidant Activity of Nicotinamide Derivatives

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The active, intact molecule is essentially destroyed before it can ever reach the bloodstream or enter the cells where it is desperately needed

Instead, alternate morning/evening or use them on non-exfoliation days
