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Rees MG, Seashore-Ludlow B, Cheah JH, Adams DJ, Price EV, Gill S, et al

BioImpacts: BI 6:33

In senescence microglia, lactate concentration is elevated, and IB, a negative regulator of NF-B, is phosphorylated and subsequently degraded, leading to activation of the NF-B pathway (Wei L

A large proportion of study participants had already been receiving intense therapies (e.g., they receive one-on-one speech and occupational therapy several times a week, as well as one-on-one ABA therapy every weekday, up to 4 h a day, for a total of 20 h of therapy per week)

BVR-A is a direct target of the IR kinase activity, and as part of a regulatory loop BVR-A phosphorylates IRS1 on inhibitory Ser residues to prevent IRS1 aberrant activation in response to IR

smegmatis produced EGT at 5.4 g/L in 96 h of fed-batch culture (Zhang et al