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190 Furthermore, the association was significant for localised tumours, but not for metastases, and was not observed in a study conducted only in men 191 or other cohorts of non-postmenopausal women or women at different physiological stages

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Increasing proportions of all prescribed pharmaceuticals are excreted into sewage and treated in waste water treatment plants

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The inhibition of ATG5, a mediator of autophagy in hypoxic cancer, can induce cisplatin sensitivity in previously resistant cells (188), supporting the contribution of hypoxia-induced autophagy to the development of anticancer drug resistance

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