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Potentially deleterious reactive oxygen species (ie, superoxides, peroxides, and hydroxyl radicals) are produced during the oxidation of fuels (oxidative phosphorylation) in mitochondria as byproducts of the utilization of molecular oxygen in the electron transport chain

[DOI] [PubMed] [Google Scholar] 11.Kumai Y

Batsis JA, Petersen CL, Cook SB, Al-Nimr RI, Driesse T, Pidgeon D, et al

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Rus GZ, Manosso LM, Quevedo J, Carvalho AF

Recently the lipid peroxidation product 4-HNE was shown to directly adduct GCLC Cys553 (and GCLM Cys35) in vitro [132]
