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Anti-inflammatory drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and minocycline, have been studied for their potential to slow the progression of Parkinson's disease

Fisetin also reduced ovarian IL-1 levels to control values and significantly suppressed NLRP3 inflammasome expression in a dose-dependent manner [122]

[42] found that mitochondrial failure causes high levels of ROS, which affects the expression of C-X-C motif chemokine ligand 14 (CXCL14) via AP-1 signaling, resulting in cell mobility via increasing intracellular Ca 2+ levels

Conversely, COX5B, MRPL33, MRPL32, and DNAJC19 genes were significantly downregulated in fulminant T1D patients

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Pharmaceutical compositions suitable for use in the present disclosure include compositions wherein the active ingredients are contained in an effective amount to achieve its intended purpose