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681 Telemedicine provides remote access to healthcare services, which is especially beneficial for patients with limited mobility or those living in remote areas

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The agency cited immunogenicity risks (peptides can trigger anti-drug antibodies with repeated injection), manufacturing impurity concerns (endotoxin contamination, truncated sequences, diastereomers), and the absence of robust human clinical data for most compounds

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The FDA-approved dosing protocol is the same regardless of sex

These two actions result in a decreased FFA flux in the liver, improving insulin and IGF-1 signalling