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However, under normal conditions, this pathway is likely to be less significant, only becoming important when MHbR activity is disrupted (58)

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Isolation of spinal cord nuclei for RNA sequencing Nuclei were isolated as previously described (Saraswathy et al ., 2023)

Studies have shown that apoptosis-promoting transcription factors such as CHOP, c-JNK, and caspase 12 are activated when cells are exposed to excessive or sustained ERS (Wang et al

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2016: 448466.e444 [Google Scholar] 27.Mustajoki P, Desnick RJ