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Collagen and Elastin Production Collagen levels decline naturally with age, resulting in skin that is thinner and less resilient

They are also expressed in vascular and lymphatic endothelia, affecting proliferation, migration, angiogenesis, as well as the formation of small lymphatic vessels and capillaries 313

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10.1111/acel.12562 74 McCutchenC

Enzyme-responsive cell-penetrating peptide conjugated mesoporous silica quantum dot nanocarriers for controlled release of nucleus-targeted drug molecules and real-time intracellular fluorescence imaging of tumor cells

A major concern is that a therapy effective for one of these objectives may be ineffectiveor even counterproductivefor another(s) of these age-related changes ( The endocrine system is the most relevant in aging