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Further, in a comparison of levels of drug-metabolizing enzymes between transgenic or knockout mice and their parental strains using Western immunoblotting, increased expression of CYP2B and CYP3A isoforms was evident in XPA gene knockout mice with no differences from parental strains for rasH2, p53(+/-), and Tg.AC mice (Ariyoshi et al

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TNF- and IL-6 activities were reported in pg/mL

Additionally, it can affect the hypothalamic axes, disrupting the secretion of sex hormones and then sperm parameters [16]

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