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The authors showed also that miR-939 overexpression downregulated PI3K-AKT pathway downstream the IGF1R and the restoration of miR-939 could represent a potential therapeutic approach for patients with osteosarcoma following the purpose of a miRNA-based targeted anticancer therapy

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10.1136/bmjopen-2019-033687 [DOI] [PMC free article] [PubMed] 11.Gramer G, Hoffmann GF (2020) Vitamin B12 deficiency in newborns and their mothersnovel approaches to early detection, treatment and prevention of a global health issue

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