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Host genetics and glycine metabolism: A mendelian randomization study showed a significant association between circulating levels of glycine and the single nucleotide polymorphism (SNP) rs715 in the 3 untranslated region of the Carbamoyl-Phosphate Synthase 1 ( CPS1 ) gene [119]

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Marques-Piubelli ML, Kumar B, Basar R, Panowski S, Srinivasan S, Norwood K, Prashad S, Szenes V, Balakumaran A, Arandhya A, Lu W, Khan K, Duenas D, McAllen S, Gomez JA, Burks JK, Acharyal S, Borthakur G , Wang WL, Wang W, Wang S, Solis LM, Marin D, Rezvani K, Daher M, Vega F

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(2015a,b), evidence was provided that central venous tracer infusion of both glucose and lactate showed massive mobilization of mainly lactatesystematic lactate was preferentially being directly consumed and used by TBI cases